This book constitutes the refereed proceedings of the 45th Annual Conference of the Southern African Computer Lecturers' Association on ICT Education, SACLA 2016, held in Cullinan, South Africa, in July 2016. The three revised full papers and 13 work-in-progress papers presented together with two invited keynote papers were carefully reviewed and selected from 30 submissions. The papers are organized in topical sections on assessment methods, instruction methods, new curricula, social skills, and various experiences.